35 Prayer For Those Who Have Lost Hope. Romans 12:12 – Rejoicing in hope; patient in tribulation; continuing instant in prayer; Are you presently at the verge of losing your hope in God, are you almost giving up on life? These prayers are for you. The fact that you searched out or found this article while surfing the internet is a great proof that God has something huge and pleasant for you in this season, so do not give up.