40 Prayers Against Affliction. What is Affliction? Affliction is when someone is in a state of pain and distress. Affliction is when someone is going through a distress which results in serious pains. NOTE: Kindly Read My Dream Interpretation Book And Other Inspiring Books… As children of God we should know that we live in a spiritual world where the spiritual controls the physical. Everything that we see happening in the physical has earlier been orchestrated and finished in the